反応 #502083

反応方程式

Boc-Lys(Cbz)-OMe

Ethyl acetate

→

Boc-Lys-OMe

溶媒

MeOH

反応条件

後処理

1. 1
   ろ過The organic solution was filtered through Celite
2. 2
   洗浄washed with 10 mL MeOH
3. 3
   その他The filtrate was evaporated under reduced pressure

実験手順

1.0 g of Boc-Lys(Cbz)-OMe (5) was dissolved in 40 mL MeOH:Ethyl acetate. 100 mg of Palladium on active carbon (Pd/C) was added to the solution. The solution was stirred under hydrogen for 2 hrs. The organic solution was filtered through Celite and washed with 10 mL MeOH. The filtrate was evaporated under reduced pressure to yield Boc-Lys-OMe of formula (6)

出典