反応 #495241

反応方程式

Metformin hydrochloride

metformin hydrochloride

magnesium stearate

→

Metformin

溶媒

water

反応条件

後処理

1. 1
   その他dried in the same device
2. 2
   その他Dried granulate
3. 3
   その他Obtained granulate
4. 4
   その他is obtained

実験手順

Metformin hydrochloride is screened through 1 mm sieve. Screened metformin hydrochloride and hydroxypropylmethylcellulose are granulated in fluid bed granulator with demineralized water and dried in the same device. Dried granulate is screened through 1 mm sieve. Obtained granulate and microcrystalline cellulose are homogenously blended in a bin blender. Pre-sieved magnesium stearate is added to the obtained blend and blended in a bin blender so that the final blend is obtained.

出典