反応 #491539

反応方程式

T23.1

Methyl 3-(2-methyl-1-propenyl)-4-(tetrahydro-2H-pyran-2-yloxy)benzoate

PPTS

→

Methyl 4-hydroxy-3-(2-methyl-1-propenyl)benzoate

収率 98.0%

T23.2

収率 98.0%

溶媒

MeOH

反応条件

後処理

1. 1
   濃縮concentrated in vacuo
2. 2
   その他The residue was purified on silica gel (0-20% EtOAc in hexanes)

実験手順

To a stirred mixture of T23.1 (0.460 g, 2 mmol) in MeOH (8 mL) was added PPTS (0.04 g, 0.2 mmol). The reaction mixture was then stirred for 24 hours and then concentrated in vacuo. The residue was purified on silica gel (0-20% EtOAc in hexanes) to yield T23.2 as a colorless oil (0.320 g, 98% yield).

出典