反応 #487521

反応方程式

6-Methoxy-naphthaldehyde

THF

→

6-methoxy-2-vinyl-naphthalene

収率 90.0%

溶媒

ether

反応条件

後処理

1. 1
   ろ過is filtered on Celite, and it
2. 2
   その他is chromatographed (hexane/AcOEt 5:1)

実験手順

6-Methoxy-naphthaldehyde (432 mg, 2.35 mmol) is added to a solution of instantaneous ylide (Ph3P+Br−+NaNH2, 1.48 g, 2.4 mmol) in anhydrous THF (5 ml). After one hour of stirring at ambient temperature, it is diluted with ether, it is filtered on Celite, and it is chromatographed (hexane/AcOEt 5:1) to obtain 6-methoxy-2-vinyl-naphthalene (390 mg, 90%).

出典