反応 #4855

反応方程式

2,3-dihydro-5,7-dinitro-2-methyl-benzofuran

methylamine

→

1-(2-methylamino-3,5-dinitrophenyl)-2-propanol

溶媒

ethanol

反応条件

後処理

1. 1
   温度After the mixture is cooled
2. 2
   その他the expected product precipitates
3. 3
   洗浄washed with alcohol
4. 4
   その他recrystallized from 50 ml of 96° strength ethanol
5. 5
   その他After being dried
6. 6
   その他0.047 mole (12 g) is obtained of a product which melts at 132° C.

実験手順

0.056 Mole (12.5 g) of 2,3-dihydro-5,7-dinitro-2-methyl-benzofuran is suspended in 100 ml of a 33% strength solution of methylamine in ethanol. After 10 hours' stirring at room temperature in a sealed Erlenmeyer, the reaction mixture is brought for 30 minutes to the refluxing temperature of the alcohol. After the mixture is cooled, the expected product precipitates. It is drained, washed with alcohol and then recrystallized from 50 ml of 96° strength ethanol. After being dried, 0.047 mole (12 g) is obtained of a product which melts at 132° C.

出典