反応 #481609

反応方程式

1-bromo-2-butanone

tetrahydrothiophene

→

2-oxobutyl-thiacyclopentanium bromide

収率 72.3%

溶媒

acetone

反応条件

後処理

1. 1
   その他After leaving for 24 hours
2. 2
   ろ過the deposited white crystal was collected by filtration
3. 3
   洗浄was washed with ether
4. 4
   その他The powder was dried by a vacuum drier at 30° C. for six hours

実験手順

In a 100 ml three-necked flask, 3.5 g of tetrahydrothiophene was dissolved in 40 ml of acetone. To the solution, 6 g of 1-bromo-2-butanone was added dropwise while stirring. After leaving for 24 hours, the deposited white crystal was collected by filtration. The white crystal was ground to a powder, which was washed with ether. The powder was dried by a vacuum drier at 30° C. for six hours to obtain 6.86 g of 2-oxobutyl-thiacyclopentanium bromide (yield: 72.2%).

出典