反応 #4814

反応方程式

KBr

benzoyl chloride

1-methylimidazole

benzaldehyde

→

1-[α-Benzoyloxybenzyl]-3-Methylimidazolium Chloride

溶媒

ether

反応条件

後処理

1. 1
   その他The resulting mixture was evaporated in vacuo
2. 2
   温度After cooling
3. 3
   その他the reaction mixture was triturated with ether
4. 4
   その他separated by filtration
5. 5
   その他Recrystallization from dichloromethane
6. 6
   その他dioxane gave 4.2 g (0.012 mol), 65%, 9, mp 199°-201°

実験手順

To an ether solution of benzoyl chloride 2.81 g (0.02 mol) there was added dropwise 1.67 g (0.02 mol) 1-methylimidazole with stirring. The resulting mixture was evaporated in vacuo and the residue was allowed to react with 2.12 g (0.02 mol) benzaldehyde at 70° overnite. After cooling, the reaction mixture was triturated with ether and was solid separated by filtration. Recrystallization from dichloromethane:dioxane gave 4.2 g (0.012 mol), 65%, 9, mp 199°-201°; ir (KBr) 1740 cm-1 ; pmr (CDCl3) δ 4.17 (s, 3H), 8.18-7.25 (m, 12H), 8.50 (s, 1H) and 11.1 (bs, 1H) ppm.

出典