反応 #48079

反応方程式

4-bromo-1-chloro-2-isopropylbenzene

3-(4-tert-butylbenzyl)-[1,2,3]oxathiazolidine 2,2-dioxide

→

desired product

収率 42.2%

(4-tert-butylbenzyl)-[2-(4-chloro-3-isopropylphenyl)-ethyl]-amine

収率 42.2%

反応条件

後処理

1. 1
   その他The residue was purified by flash column chromatography

実験手順

The title compound was synthesized in analogy to example S6-C using 4-bromo-1-chloro-2-isopropylbenzene (120 mg, 0.51 mmol), and 3-(4-tert-butylbenzyl)-[1,2,3]oxathiazolidine 2,2-dioxide (138 mg, 0.51 mmol). The residue was purified by flash column chromatography to give the desired product (74 mg, 42%) as a light yellow oil. MS (ISP) 344.3 (M+H)+.

出典