反応 #4715

反応方程式

methylisocyanate

N-[3-[3-(1-piperidinylmethyl)phenoxy]-propyl]-hydrazine carboxamide

→

N-Methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,2-hydrazine dicarboxamide

溶媒

THF

反応条件

後処理

1. 1
   ろ過The precipitate is filtered off
2. 2
   その他recrystallised from methanol

実験手順

0.8 ml (13 mmol) of methylisocyanate are added to 2.0 g (6.6 mmol) of N-[3-[3-(1-piperidinylmethyl)phenoxy]-propyl]-hydrazine carboxamide in 20 ml of THF and the reaction mixture is stirred at room temperature for one hour. The precipitate is filtered off and recrystallised from methanol. The analytical values are summarized in Table I.

出典