反応 #470413

反応方程式

4′,7-Dihydroxyisoflav-3-ene

ethanol

Methylamine

formaldehyde

→

title compound

収率 79.0%

4-(3-Methyl-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

収率 79.0%

反応条件

後処理

1. 1
   その他The white precipitate was collected

実験手順

4′,7-Dihydroxyisoflav-3-ene (507 mg, 2.11 mmol) was dissolved in ethanol (20 ml). Methylamine solution (0.6 ml, 4.82 mmol, 33% wt. in ethanol) was added followed by formaldehyde solution (2 ml, 0.03 mol, 37% wt.). The reaction was stirred at room temperature for 1 day. The white precipitate was collected to afford the title compound (490 mg, 79%).

出典