反応 #470396

反応方程式

N-(2-nitrophenyl)biphenyl-2-amine

hydrogen

→

N1-(biphenyl-2-yl)benzene-1,2-diamine

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過The solution was filtered through Celite
2. 2
   その他to remove the catalyst, Celite
3. 3
   洗浄was washed with dichloromethane
4. 4
   その他the filtrate was evaporated
5. 5
   その他to yield a brown oil, 14.8 g (84%)
6. 6
   その他The product was used for the next step without further purification

実験手順

N-(2-nitrophenyl)biphenyl-2-amine (19.69 g, 67.8 mmol), 10% palladium on carbon (0.29 g, 0.27 mmol), and 150 mL of ethanol was added to a Parr hydrogenator bottle. The mixture was hydrogenated on a Parr hydrogenator until no more hydrogen was taken up by the solution. The solution was filtered through Celite to remove the catalyst, Celite was washed with dichloromethane, the filtrate was evaporated to yield a brown oil, 14.8 g (84%). The product was used for the next step without further purification.

出典