反応 #470389

反応方程式

2-isopropyl-N-(2-nitrophenyl)aniline

hydrogen

→

desired product

収率 99.3%

N1-(2-isopropylphenyl)benzene-1,2-diamine

収率 99.3%

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過The catalyst was filtered off through a Celite bed
2. 2
   その他The solvent was evaporated
3. 3
   その他The product was used for the next step without further purification

実験手順

2-isopropyl-N-(2-nitrophenyl)aniline (22.7 g, 89 mmol) and 10% palladium on carbon (0.6 g) were mixed with 150 mL of ethanol under nitrogen in a plastic coated hydrogenation vessel. The mixture was put on a par hydrogenator and reacted under 40 psi of hydrogen until there is no pressure drop. The catalyst was filtered off through a Celite bed. The solvent was evaporated. The product was used for the next step without further purification. 20 g of desired product was obtained.

出典