反応 #470369

反応方程式

trifluoromethanesulfonic acid

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methoxymethyl-N-Methylpyrrolidinium Chloride

→

trifluoromethanesulfonic acid

desired product

N-Methoxymethyl-N-Methylpyrrolidinium

溶媒

methanol

methanol

MeOH

反応条件

後処理

1. 1
   その他to remove hydrogen chloride
2. 2
   その他produced as a by-product

実験手順

A 30.0 g quantity of N-methoxymethyl-N-methylpyrrolidinium chloride prepared in Example 10 was dissolved in 30.0 g of MeOH, and 80.0 g of methanol solution of 35 wt. % trifluoromethanesulfonic acid was added to the solution. The mixture was heated at 130° C. in a nitrogen stream to remove hydrogen chloride produced as a by-product, an excess of trifluoromethanesulfonic acid and methanol, giving 49.0 g of the desired product.

出典