反応 #470368

反応方程式

sodium acetate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Acetate

溶媒

methanol

反応条件

後処理

1. 1
   その他The mixture was reacted at room temperature for 1.5 hours
2. 2
   その他whereby the reaction was terminated
3. 3
   ろ過The reaction mixture was filtered
4. 4
   濃縮the filtrate was concentrated
5. 5
   その他dried in a vacuum
6. 6
   workup.ADDITIONTo the residue was added 100 ml of dichloromethane
7. 7
   ろ過followed by filtration with a membrane
8. 8
   ろ過filter
9. 9
   濃縮concentration in a vacuum
10. 10
    その他drying

実験手順

A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.

出典