反応 #470365

反応方程式

sodium perchlorate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Perchlorate

溶媒

ethyl alcohol

反応条件

後処理

1. 1
   その他The mixture was reacted at room temperature for 1.5 hours
2. 2
   その他whereby the reaction was terminated
3. 3
   ろ過The resulting sodium chloride was filtered off
4. 4
   濃縮the filtrate was concentrated
5. 5
   その他dried in a vacuum
6. 6
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane
7. 7
   ろ過the solution was again filtered with a membrane
8. 8
   ろ過filter
9. 9
   濃縮the filtrate was concentrated in a vacuum
10. 10
    その他dried

実験手順

A 5.91 g quantity of sodium perchlorate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 77 g of ethyl alcohol, and 7.99 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The resulting sodium chloride was filtered off, and the filtrate was concentrated and dried in a vacuum. The residue was dissolved in dichloromethane, the solution was again filtered with a membrane filter, and the filtrate was concentrated in a vacuum and dried, giving 10.94 g of the desired product.

出典