反応 #470364

反応方程式

sodium carbonate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Carbonate

溶媒

water

反応条件

後処理

1. 1
   その他The mixture was reacted at room temperature for 0.5 hour
2. 2
   その他whereby the reaction was terminated
3. 3
   濃縮The reaction mixture was concentrated
4. 4
   乾燥dried in vacuum, and 100 ml of ethyl alcohol
5. 5
   workup.ADDITIONwas added to the residue
6. 6
   その他to remove insoluble sodium chloride
7. 7
   workup.DISSOLUTIONThe resulting product was dissolved in dichloromethane
8. 8
   ろ過the solution was filtered with a membrane
9. 9
   ろ過filter again
10. 10
    濃縮the filtrate was concentrated in a vacuum
11. 11
    その他dried

実験手順

A 1.60 g quantity of sodium carbonate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 18 g of deionized water, and 5.01 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 0.5 hour, whereby the reaction was terminated. The reaction mixture was concentrated and dried in vacuum, and 100 ml of ethyl alcohol was added to the residue to remove insoluble sodium chloride. The resulting product was dissolved in dichloromethane, the solution was filtered with a membrane filter again, and the filtrate was concentrated in a vacuum and dried, giving 5.41 g of the desired product.

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