反応 #4700

反応方程式

hydrazine hydrate

2-methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine

diphenylcarbonate

→

N-[2-Methyl-3-[3-(1-piperidinylmethyl)phenoxy]propyl]hydrazine carboxamide

溶媒

ethanol

反応条件

後処理

1. 1
   温度the reaction mixture is heated
2. 2
   温度under reflux for one hour

実験手順

2.2 g (8 mmol) of 2-methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine in 20 ml of ethanol are stirred together with 1.9 g (8 mmol) of diphenylcarbonate at room temperature for 12 hours. 4 g of hydrazine hydrate is then added to the solution and the reaction mixture is heated under reflux for one hour. Isolation of the product is carried out as described in Example 1.

出典