反応 #46786

反応方程式

4-Chloro-phenylamine

pyridine

bromo-acetyl bromide

→

2-Bromo-N-(4-Chloro-phenyl)-acetamide

溶媒

toluene

toluene

反応条件

後処理

1. 1
   workup.ADDITIONwere added dropwise under ice cooling
2. 2
   その他After 2 h the precipitate was isolated by filtration
3. 3
   その他recrystallized from toluene
4. 4
   その他to yield a white solid

実験手順

To a solution of 5 g 4-Chloro-phenylamine and 1.5 mL pyridine in 30 mL toluene, 8 g bromo-acetyl bromide dissolved in 10 mL toluene were added dropwise under ice cooling. After 2 h the precipitate was isolated by filtration and recrystallized from toluene to yield a white solid.

出典