反応 #46320

反応方程式

HCl

compound

(±)-cis 1-Hydroxy-6-methoxy-3,3,14-trimethyl-7-oxo-2,3,7,14-tetrahydro-1H-benzo[b]chromeno[6,5-g][1,8]naphthyridin-2-yl butyrate

→

6-Methoxy-3,3,14-trimethyl-7-oxo-7,14-dihydro-3H-benzo[b]chromeno[6,5-g][1,8]naphthyridin-2-yl butyrate

溶媒

dichloromethane

反応条件

後処理

1. 1
   その他dried
2. 2
   濃縮concentrated under reduced pressure
3. 3
   その他to be isolated

実験手順

Add 4 drops of a 10% solution of HCl to a solution of 0.29 mmol of the compound of Example 13 in 6 ml of dichloromethane. The reaction mixture is stirred for 3 days at ambient temperature and then dried and concentrated under reduced pressure. Chromatography of the residue on silica gel (dichloromethane/methanol gradient) allows the expected product to be isolated.

出典