反応 #4629

反応方程式

5-(2-bromoethoxy)salicylamide

1-(2-allyloxyphenoxy)-3-aminopropan-2-ol

→

1-(2-allyloxyphenoxy)-3-[2-(3-carbamoyl-4-hydroxyphenoxy)ethylamino]propan-2-ol

溶媒

isopropanol

反応条件

後処理

1. 1
   その他is melted in an oil bath at 100°

実験手順

A mixture of 6.5 g of 5-(2-bromoethoxy)salicylamide and 8.9 g of 1-(2-allyloxyphenoxy)-3-aminopropan-2-ol is melted in an oil bath at 100° and stirred for 1 hour using a magnetic stirrer. The working up is carried out analogously to Example 11 and yields 1-(2-allyloxyphenoxy)-3-[2-(3-carbamoyl-4-hydroxyphenoxy)ethylamino]propan-2-ol having a melting point of 147°-148° (from isopropanol).

出典