反応 #4526

反応方程式

methylamine

1,2,2,2-tetrachloroethyl chloroformate

→

1,2,2,2-tetrachloroethyl N-methylcarbamate

溶媒

dichloromethane

反応条件

後処理

1. 1
   洗浄The organic phase is washed with 2×100 ml of water
2. 2
   乾燥dried over magnesium sulphate

実験手順

34.7 ml (0.4 mmol) of methylamine (in 40% strength aqueous solution) are added dropwise to a solution maintained at 0° C. of 49.4 g (0.2 mole) of 1,2,2,2-tetrachloroethyl chloroformate in dichloromethane (150 ml). The mixture is then stirred for 2 hours at room temperature. The organic phase is washed with 2×100 ml of water and dried over magnesium sulphate.

出典