反応 #452424

反応方程式

N-(4-fluorobenzoyl)-4-nitroaniline

→

N-(4-fluoro-benzoyl)-4-aminoaniline

収率 79.0%

溶媒

tetrahydrofuran

反応条件

後処理

1. 1
   ろ過The reaction mixture was then filtered
2. 2
   濃縮the filtrate concentrated under reduced pressure

実験手順

A mixture of 32.25 gm (124 mMol) N-(4-fluorobenzoyl)-4-nitroaniline and 3.2 gm platinum on carbon in 500 mL tetrahydrofuran was hydrogenated at room temperature for 18 hours with an initial pressure of 60 p.s.i. The reaction mixture was then filtered and the filtrate concentrated under reduced pressure to give 22.45 gm (79%) of N-(4-fluoro-benzoyl)-4-aminoaniline.

出典