反応 #452414

反応方程式

n-butyl bromide

NaHCO3

m-aminophenol

→

3-(n-butylamino)phenol

収率 57.0%

溶媒

methanol

反応条件

後処理

1. 1
   温度the mixture is refluxed for 5 h
2. 2
   温度After cooling
3. 3
   ろ過it is filtered
4. 4
   その他the solvent is removed in vacuo

実験手順

0.11 mol of n-butyl bromide and 0.1 mol NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-butylamino)phenol.

出典