反応 #44975

反応方程式

Trans-4-(aminomethyl)cyclohexanecarboxylic acid

thionyl chloride

methanol

→

methyl trans-4-(aminomethyl)-cyclohexanecarboxylate hydrochloride

反応条件

後処理

1. 1
   温度cooling
2. 2
   濃縮concentrated under reduced pressure to dryness

実験手順

Trans-4-(aminomethyl)cyclohexanecarboxylic acid (6.29 g) is suspended in methanol (32 ml) and thereto is added dropwise thionyl chloride (6 ml) under ice-cooling. The reaction solution is warmed to room temperature, stirred overnight and concentrated under reduced pressure to dryness to give methyl trans-4-(aminomethyl)-cyclohexanecarboxylate hydrochloride (8.69 g).

出典