反応 #449656

ord-1115f63737674e86ba475dd5b5e8555d

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In this reaction scheme, methyl 6-bromohexanoate is alkylated with methyl glycine in the presence of sodium hydride to afford the 6-[(carboxymethyl)amino]hexanoic acid. Treatment of 6-[(carboxymethyl)amino]hexanoic acid with sodium hydroxide affords the corresponding 6-[(carboxymethyl)amino]hexanoic acid disodium salt.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05869527uspto-grants-1999_02