反応 #44875

反応方程式

tert-butyl [(4-hydroxypiperidin-4-yl)methyl]carbamate

methyl 1-(iodomethyl)cyclohexanecarboxylate

→

title compound

Methyl 1-[(4-{[(tert-butoxycarbonyl)amino]methyl}-4-hydroxypiperidine-1-yl)methyl]cyclohexanecarboxylate

反応条件

実験手順

The title compound was prepared by a method similar to that shown in the Step 2 of Example 3 by using tert-butyl [(4-hydroxypiperidin-4-yl)methyl]carbamate (Chem. Pharm. Bull., 2002, 50 (9) 1187-1194) and methyl 1-(iodomethyl)cyclohexanecarboxylate (Step 1 of Example 6).

出典