反応 #4478

反応方程式

1,3-Cyclohexanedione

product

[4-(Phenylmethoxy)phenyl]hydrazine hydrochloride

→

title compound

収率 38.4%

1,2,3,9-Tetrahydro-6-(phenylmethoxy)-4H-carbazol-4-one

収率 38.4%

溶媒

ethanol

water

water

反応条件

後処理

1. 1
   温度heated
2. 2
   温度to reflux for 14 h
3. 3
   温度to cool
4. 4
   ろ過the precipitate filtered
5. 5
   洗浄washed with isopropyl acetate and ether
6. 6
   その他to give a solid
7. 7
   その他Recrystallisation from methanol

実験手順

1,3-Cyclohexanedione (3.1 g) and the product of Stage (i) (5.6 g) in ethanol (196 ml) and water (39 ml) was stirred at room temperature for 3 h and then heated to reflux for 14 h. The resulting solution was allowed to cool, poured into water (500 ml) and the precipitate filtered and washed with isopropyl acetate and ether to give a solid. Recrystallisation from methanol gave the title compound as a solid (2.5 g) m.p. 235°-237°.

出典