反応 #4473

反応方程式

product

1,3-Cyclohexanedione mono(4-bromophenylhydrazone)

water

→

title compound

6-Bromo-1,2,3,9-tetrahydro-4H-carbazol-4-one

溶媒

acetic acid

反応条件

後処理

1. 1
   温度The mixture was cooled
2. 2
   ろ過the resulting solid filtered off
3. 3
   その他dried (0.95 g)
4. 4
   その他Purification by flash chromatography (E)

実験手順

The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65

出典