反応 #44675

反応方程式

3-amino-1,2-benzisoxazol-4-ol

3,4-difluoronitrobenzene

potassium carbonate

→

4-(2-Fluoro-4-nitrophenoxy)-1,2-benzisoxazole-3-amine

溶媒

dimethylformamide

water

反応条件

後処理

1. 1
   ろ過the precipitate is filtered off
2. 2
   その他The product is dried under high vacuum

実験手順

94.37 mg (0.63 mmol) of 3-amino-1,2-benzisoxazol-4-ol (from example V), 100 mg (0.63 mmol) of 3,4-difluoronitrobenzene and 95.56 mg (0.69 mmol) of potassium carbonate are suspended in 3 ml of anhydrous dimethylformamide and stirred at room temperature for 16 hours. The reaction solution is then diluted with water, and the precipitate is filtered off. The product is dried under high vacuum.

出典