反応 #444877

反応方程式

2,3,4,5-tetrafluorobenzotrichloride

carbon monoxide

hydrogen chloride

→

2,3,4,5-tetrafluorobenzoyl chloride

溶媒

formic acid

反応条件

後処理

1. 1
   workup.ADDITIONwere added
2. 2
   その他were pumped in over 8 hours at 60° C
3. 3
   workup.ADDITIONAfter addition
4. 4
   workup.DISTILLATIONThe product was then distilled

実験手順

268 g of 2,3,4,5-tetrafluorobenzotrichloride were placed in a stirred apparatus and 5.3 [lacuna] of iron(III) chloride were added, 45 g of formic acid (98-100%) were pumped in over 8 hours at 60° C. Vigorous gas development (carbon monoxide, hydrogen chloride) began immediately. The gas stream was fed to an absorption tower via a cooler. After addition was complete, the mixture was stirred until the end of gas development. The product was then distilled. 195 g of 2,3,4,5-tetrafluorobenzoyl chloride were obtained (91.5% of theory); b.p.: 70°-72° C./20 mbar, nD25 : 1.4773.

出典