反応 #440626

ord-bcf25d7a40294a44a029a042fffb7e3f

反応方程式

COC(=O)c1cnn(-c2ccc(S(C)(=O)=O)cc2Cl)c1C1CC1
5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid methyl ester
N=C(N)N
guanidine
→
CS(=O)(=O)c1ccc(-n2ncc(C(=O)NC(=N)N)c2C2CC2)c(Cl)c1
N-{5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carbonyl}-guanidine

反応物

COC(=O)c1cnn(-c2ccc(S(C)(=O)=O)cc2Cl)c1C1CC1
5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid methyl ester
N=C(N)N
guanidine

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

coupling said 5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid methyl ester with guanidine to form N-{5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carbonyl}-guanidine.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06753334B2uspto-grants-2004_06