反応 #440597

ord-40e44a99cc40499eb49b38c3155ba917

反応方程式

C1=CC2CCC1C2
norbornene
CC(C)(C)OC(=O)C1CC2CC1C1C3C=CC(C3)C21
8-t-butoxycarbonyltetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
CC(C)(C)OC(=O)C1C2C=CC(C2)C1C(=O)OC(C)(C)C
5,6-di(t-butoxycarbonyl)norbornene
CC(C)(C)OC(=O)COC(=O)C1C2C=CC(C2)C1C(=O)OCC(=O)OC(C)(C)C
5,6-di(t-butoxycarbonylmethoxycarbonyl)norbornene
C1=CC2CC1C1C3CCC(C3)C21
tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
C1=CC2CC1C1C3CCC(C3)C21
tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
CC(C)(C)OC(=O)C1CC2C=CC1C2
5-t-butoxycarbonylnorbornene
→
O=C(OC1CCCCO1)C1C2CC(C1C(=O)OC1CCCCO1)C1C3C=CC(C3)C21
8,9-di(tetrahydropyranyloxycarbonyl)tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene

反応物

C1=CC2CCC1C2
norbornene
CC(C)(C)OC(=O)C1CC2CC1C1C3C=CC(C3)C21
8-t-butoxycarbonyltetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
CC(C)(C)OC(=O)C1C2C=CC(C2)C1C(=O)OC(C)(C)C
5,6-di(t-butoxycarbonyl)norbornene
CC(C)(C)OC(=O)COC(=O)C1C2C=CC(C2)C1C(=O)OCC(=O)OC(C)(C)C
5,6-di(t-butoxycarbonylmethoxycarbonyl)norbornene
C1=CC2CC1C1C3CCC(C3)C21
tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
C1=CC2CC1C1C3CCC(C3)C21
tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
CC(C)(C)OC(=O)C1CC2C=CC1C2
5-t-butoxycarbonylnorbornene

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Of these norbornene derivativeses (β-1), 5-t-butoxycarbonylnorbornene, 5,6-di(t-butoxycarbonyl)norbornene, 5,6-di(t-butoxycarbonylmethoxycarbonyl)norbornene, 8-t-butoxycarbonyltetracyclo[4.4.0.12,5.17,10]dodeca-3-ene, 8-methyl-8-t-butoxycarbonyl)tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene, 8-methyl-8-t-butoxycarbonylmethoxycarbonyl)tetracyclo[4.4.0.12,5.17,10]dodeca-3-ene, and the like are preferable.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06753124B2uspto-grants-2004_06