反応 #439111

反応方程式

ethyl 3-phenyl-3-(6-hydroxyindol-3-yl)propionate

4-bromo-1-butanol

potassium carbonate

→

ethyl 3-phenyl-3-[6-(4-hydroxybutoxy)indol-3-yl]propionate

溶媒

acetone

反応条件

実験手順

Analogously to Example 1.4, 1.2 g (3.88 mmol) of ethyl 3-phenyl-3-(6-hydroxyindol-3-yl)propionate are reacted with 1.16 g (7.6 mmol) of 4-bromo-1-butanol in the presence of 2.1 g (15.2 mmol) of potassium carbonate in 30 ml of acetone, giving ethyl 3-phenyl-3-[6-(4-hydroxybutoxy)indol-3-yl]propionate.

出典