反応 #43887

反応方程式

2,7-Biscarboethoxyamino-9-phenylphenanthridine

3-bromopropionic acid

→

product 22-2

10-Carboxyethyl-2,7-biscarboethoxyamino-9-phenylphenanthridine

溶媒

nitrobenzene

反応条件

後処理

1. 1
   その他is precipitated by addition of ether

実験手順

2,7-Biscarboethoxyamino-9-phenylphenanthridine (22-1, 1 equiv.), prepared by the method of Watkins (1952) J. Chem. Soc. 3059, is combined with 3-bromopropionic acid (2.5 equiv.; Aldrich Chemical Co., Milwaukee, Wis.) and is heated in nitrobenzene at 100° C. for 4-6 hours. Following cooling to room temperature the crude product is precipitated by addition of ether. The product 22-2 is isolated by filtration and used directly.

出典