反応 #43663

反応方程式

Clopidogrel

Benzenesulfonic acid

→

title compound

Clopidogrel Besylate

溶媒

methanol

反応条件

後処理

1. 1
   その他to obtain a clear solution
2. 2
   温度The reaction mixture was heated
3. 3
   温度to reflux temperature for 2 to 10 hrs
4. 4
   その他The solvent was evaporated to dryness under reduced pressure

実験手順

Clopidogrel base was dissolved in methanol to obtain a clear solution. Benzenesulfonic acid was added to the solution at 20° C. The reaction mixture was heated to reflux temperature for 2 to 10 hrs. The solvent was evaporated to dryness under reduced pressure to obtain the title compound.

出典