反応 #43610

反応方程式

2,3-Dihydrofuro[2,3-c]pyridin-5-ylmethanol

→

desired compound

収率 70.0%

2,3-Dihydrofuro[2,3-c]pyridine-5-carbaldehyde

収率 70.0%

溶媒

dichloromethane

反応条件

後処理

1. 1
   ろ過The mixture was filtered through kieselguhr
2. 2
   その他the filtrate evaporated to dryness

実験手順

2,3-Dihydrofuro[2,3-c]pyridin-5-ylmethanol (1.31 g, 8.7 mmol) was dissolved in dichloromethane (100 ml) and treated with manganese dioxide (6 g, 69 mmol) at ambient temperature with vigorous stirring for 18 h. The mixture was filtered through kieselguhr and the filtrate evaporated to dryness to provide the desired compound (0.9 g, 70%).

出典