反応 #4361

反応方程式

ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)-acetate

triethyl orthoformate

acetic anhydride

→

Ethyl 2-(2,4-dichloro-5-fluoro-3-nitro-benzoyl)-3-ethoxyacrylate

反応条件

後処理

1. 1
   濃縮The mixture is then concentrated in vacuo and 270 g of ethyl benzoyl-ethoxy-acrylate
2. 2
   その他are obtained as an oily residue

実験手順

244.8 g of ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)-acetate are heated at 150°-160° C. with 166 g of triethyl orthoformate and 185 g of acetic anhydride for 3 hours. The mixture is then concentrated in vacuo and 270 g of ethyl benzoyl-ethoxy-acrylate are obtained as an oily residue.

出典