反応 #4358

反応方程式

2,4,5-trifluorobenzoic acid

3-chloro-2,4,5-trifluorobenzoic acid

thionyl chloride

→

3-chloro-2,4,5-trifluorobenzoyl chloride

溶媒

反応条件

実験手順

Chlorination of 2,4,5-trifluorobenzoic acid in chlorosulphonic acid leads to 3-chloro-2,4,5-trifluorobenzoic acid, which is reacted as a crude product with thionyl chloride to give 3-chloro-2,4,5-trifluorobenzoyl chloride (boiling point 94°/18 mbar; nD20 =1.5164): ##STR10##

出典