反応 #4336

反応方程式

2,5-dibromo-4-nitroaniline

compound B

2,5-dibromo-4-nitroaniline

ethanolamine

→

2-β-hydroxyethylamino-4-amino-5-bromonitrobenzene

溶媒

ethanol

反応条件

後処理

1. 1
   workup.ADDITIONhave been added
2. 2
   温度The mixture is heated
3. 3
   温度After cooling
4. 4
   その他dilution of the reaction mixture with 100 ml of iced water, the expected product precipitates

実験手順

0.02 mole (5.92 g) of 2,5-dibromo-4-nitroaniline (compound B) is added to 15 ml of 96° ethanol to which 12 ml of ethanolamine have been added. The mixture is heated in refluxing alcohol for 6 h 30 min. After cooling and dilution of the reaction mixture with 100 ml of iced water, the expected product precipitates.

出典