反応 #433114

反応方程式

4-(4-(2-quinolinylmethylthio)phenoxymethyl)benzoic acid

m-chloroperbenzoic acid

potassium hydrogen carbonate

→

4-(4-(2-quinolinylmethylsulfinyl)phenoxymethyl)benzoic acid

溶媒

dichloroethene

反応条件

後処理

1. 1
   その他The reaction is assayed by TLC and upon consumption of the starting thio compound
2. 2
   ろ過the mixture is filtered
3. 3
   洗浄washed with dilute aqueous sodium bisulfite
4. 4
   その他dried
5. 5
   その他evaporated

実験手順

4-(4-(2-quinolinylmethylthio)phenoxymethyl)benzoic acid (4 mmol) in dichloroethene (50 ml) is stirred with m-chloroperbenzoic acid (4 mmol) and solid potassium hydrogen carbonate (1.0 g). The reaction is assayed by TLC and upon consumption of the starting thio compound, the mixture is filtered, washed with dilute aqueous sodium bisulfite, dried and evaporated to give 4-(4-(2-quinolinylmethylsulfinyl)phenoxymethyl)benzoic acid.

出典