反応 #4329

反応方程式

sulphuric acid

2,5-dibromo-4-nitro-N-benzenesulphonylaniline

→

2,5-dibromo-4-nitroaniline

溶媒

water

water

反応条件

後処理

1. 1
   その他rises to 70° C
2. 2
   温度The temperature is maintained at 70°-78° C. for 2 hours
3. 3
   その他the expected product precipitates
4. 4
   ろ過After filtration
5. 5
   洗浄washing to neutrality the product
6. 6
   その他is recrystallized from 450 ml of ethanol

実験手順

15 ml of water are added, with due care, to 115 ml of concentrated sulphuric acid; the temperature rises to 70° C. 0.105 mole (46 g) of 2,5-dibromo-4-nitro-N-benzenesulphonylaniline are then added. The temperature is maintained at 70°-78° C. for 2 hours. The reaction mixture is poured into 1 kg of ice and water; the expected product precipitates. After filtration and washing to neutrality the product is recrystallized from 450 ml of ethanol. It melts at 178° C.

出典