反応 #4328

反応方程式

acetic acid

sodium nitrite

2,5-dibromo-N-benzenesulphonylaniline

nitric acid

→

2,5-dibromo-4-nitro-N-benzenesulphonylaniline

溶媒

water

反応条件

後処理

1. 1
   workup.ADDITIONare added
2. 2
   温度The reaction mixture, cooled beforehand
3. 3
   その他the expected product precipitates
4. 4
   ろ過It is filtered off
5. 5
   洗浄washed to neutrality
6. 6
   その他recrystallized from acetic acid

実験手順

To 250 ml of acetic acid, diluted with 130 ml of water, are added: 1.5 g of sodium nitrite, 0.13 mole of 2,5-dibromo-N-benzenesulphonylaniline prepared in the previous stage and 0.78 mole (32.5 ml) of nitric acid (d=1.52). The reaction mixture is heated for 1 hour at 90° C. The reaction mixture, cooled beforehand, is poured onto 1 kg of ice and the expected product precipitates. It is filtered off, washed to neutrality and then recrystallized from acetic acid; it melts at 148° C.

出典