反応 #430086

反応方程式

2-(tributylstannyl)thiophene

2,7-dibromo-9,9-di-n-decyl-9H-fluorene

→

compound

収率 70.0%

2,7-bis-(2-thienyl)-9,9-di-(n-decyl)-9H-fluorene

収率 70.0%

溶媒

toluene

反応条件

後処理

1. 1
   その他equipped with a condenser and a magnetic stir bar that
2. 2
   その他had been previously dried in an oven at 110° C
3. 3
   workup.DISTILLATIONhad been freshly distilled
4. 4
   その他degassed with nitrogen
5. 5
   洗浄the beaker rinsed twice with 3 ml portions of degassed toluene
6. 6
   温度the solution refluxed until it
7. 7
   その他The toluene was removed under reduced pressure
8. 8
   workup.DISSOLUTIONthe residue dissolved in hexane
9. 9
   その他The organic layer was separated
10. 10
    洗浄washed twice with an equal volume of water
11. 11
    乾燥dried over anhydrous MgSO4
12. 12
    ろ過filtered
13. 13
    濃縮concentrated
14. 14
    その他The crude product was purified by column chromotography on silica gel

実験手順

2-(tributylstannyl)thiophene (5.80 ml, 0.018 mol) was added under nitrogen directly to a single-necked round bottom flask equipped with a condenser and a magnetic stir bar that had been previously dried in an oven at 110° C. The 2,7-dibromo-9,9-di-n-decyl-9H-fluorene (5.26 g, 8.70 mmol) was weighed into a beaker and dissolved in toluene (14 ml) which had been freshly distilled and degassed with nitrogen. The resulting fluorene solution was pipetted into the round bottom flask and the beaker rinsed twice with 3 ml portions of degassed toluene. Pd(PPh3)4 (0.50 g, 0.43 mmol) and PdCl2 (PPh3)2 (0.31 g, 0.44 mmol) were added to the reaction flask and the solution refluxed until it turned black. The toluene was removed under reduced pressure and the residue dissolved in hexane. The hexane solution was stirred vigorously with a 100 ml of a 2% aqueous KF solution for 3 hours. The organic layer was separated, washed twice with an equal volume of water, dried over anhydrous MgSO4, filtered and concentrated. The crude product was purified by column chromotography on silica gel using hexane as the eluent. The purified waxy solid compound (mp 59.9°-60.8° C.) was isolated in a 70% yield. Mass Spec. m/z 610 (M+), 469 (M--C10H21), Elemental Analysis: Calculated for C41H52S2 : C, 80.60, H, 8.91, S, 10.49. Found: C, 80.55, H, 8.97, S, 10.08.

出典