反応 #429625

反応方程式

2-ethyl-3-methyl-7-nitrobenzo[b]furan

→

7-amino-2-ethyl-3-methylbenzo[b]furan

収率 100.5%

溶媒

methanol

dioxane

反応条件

後処理

1. 1
   ろ過The catalyst was filtered off
2. 2
   その他the filtrate was evaporated in vacuo

実験手順

To a solution of 2-ethyl-3-methyl-7-nitrobenzo[b]furan (1.00 g) in a mixture of methanol (15 ml) and dioxane (10 ml) was added 10% palladium carbon (100 mg) and the above mixture was hydrogenated at 3 atom for 1 hour. The catalyst was filtered off and the filtrate was evaporated in vacuo to give 7-amino-2-ethyl-3-methylbenzo[b]furan (858 mg) as an oil.

出典