反応 #42865

反応方程式

dehydrocavidine dehydroapocavidine

aluminum oxide

aluminum oxide

→

dehydrocavidine

収率 24.3%

反応条件

後処理

1. 1
   洗浄a gradient elution
2. 2
   workup.ADDITIONThe eluate containing dehydrocavidine
3. 3
   濃縮is concentrated by decompression to constant weight

実験手順

10 g of the dehydrocavidine-dehydroapocavidine composition obtained from the above step is mixed with 40 g of the aluminum oxide, and are then added to the top of an aluminum oxide column, and a gradient elution is employed with a solvent system of petroleum ether: ethyl acetate (1:8˜1:15) accompanied by TLC tracking. The eluate containing dehydrocavidine is combined and then is concentrated by decompression to constant weight, resulting in a 1.3 g dehydrocavidine compound and a 1.9 g dehydroapocavidine compound respectively.

出典