反応 #426328

反応方程式

L-Carnitine

acetylsalicylic acid

→

L-carnitine Acetylsalicylic Acid

溶媒

ethanol

反応条件

後処理

1. 1
   濃縮the solution concentrated in vacuo at about 40° C. till syrup consistence that
2. 2
   温度on cooling
3. 3
   その他crystallizes
4. 4
   その他The crystalline mass was triturated with acetone (50 ml)
5. 5
   ろ過filtered
6. 6
   洗浄washed with acetone
7. 7
   その他dried in vacuo at room temperature

実験手順

L-Carnitine (1.61 g, 10 mmol) and acetylsalicylic acid (1.80 g, 10 mmol) were dissolved in ethanol (20 ml) and the solution concentrated in vacuo at about 40° C. till syrup consistence that on cooling crystallizes. The crystalline mass was triturated with acetone (50 ml), filtered, washed with acetone and dried in vacuo at room temperature. The yield of colorless crystals with m.p. 90-94° C. was 3.17 g (93%). The substance is water soluble, stable at ambient conditions.

出典