反応 #425376

反応方程式

N-formyl-2-amino-3′,5-di-t-butyl biphenyl

di-t-butyl peroxide

→

2,9-di-tert-butylphenanthridinone

溶媒

chlorobenzene

反応条件

後処理

1. 1
   workup.ADDITIONwas added
2. 2
   濃縮The reaction mixture was concentrated in half
3. 3
   温度cooled to 0° C
4. 4
   その他The precipitate that formed
5. 5
   ろ過was collected by vacuum filtration
6. 6
   洗浄The off-white solid was washed with hexanes

実験手順

The above compound, N-formyl-2-amino-3′,5-di-t-butyl biphenyl (6.5 g, 21 mmol) was dissolved into 50 mL of chlorobenzene to which 5 equivalents of di-t-butyl peroxide was added. The reaction mixture was heated to 110° C. for 72 hours. The reaction mixture was concentrated in half and cooled to 0° C. The precipitate that formed was collected by vacuum filtration. The off-white solid was washed with hexanes to give 2,9-di-tert-butylphenanthridinone as determined by GCMS and not purified any further.

出典