反応 #42355

ord-92306b3288f94584930245ab3ab8e0d5

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    濃縮The solution is concentrated under reduced pressure

実験手順

To O-benzyl-N-(tert-butoxycarbonyl)homoserine (5.8 g, 18.9 mmol) in 20% methanol/benzene (72 mL) is added 2M trimethylsilyldiazomethane in hexane (12.3 mL, 24.5 mmol), and the reaction stirred at room temperature 1.5 h. The solution is concentrated under reduced pressure to give the title compound in pure form. ESI MS m/z 324.2 [M+H]+.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07727997B2uspto-grants-2010_06