反応 #4218

反応方程式

Meta-chlorobenzaldehyde

1-(3-trifluoromethyl-4-fluorophenylamino)-2-butanol

→

2-m-Chlorophenyl-3-(3-trifluoromethyl-4-fluorophenyl)-5-ethyl oxazolidine

反応条件

後処理

1. 1
   workup.ADDITIONwas added
2. 2
   温度The mixture was heated on the steam bath for about one hour
3. 3
   その他stripped on the rotary evaporator

実験手順

Meta-chlorobenzaldehyde (2.3 g, 0.016 mole) was combined with 5 g of 1-(3-trifluoromethyl-4-fluorophenylamino)-2-butanol and 3 drops of methane sulfonic acid was added. The mixture was heated on the steam bath for about one hour and stripped on the rotary evaporator. The product, a sticky, thick liquid, was characterized by IR and NMR.

出典