反応 #42031

ord-ebdcd0e623e0424faeb25cf24b8c0305

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他obtained in the step 3

実験手順

This compound was prepared in the same manner as in Reference Example 1 (step 6), except that ethyl 4-(4-methylpiperazin-1-ylmethyl)-3-trifluoromethylbenzoate obtained in the step 3 was used, and that the reaction solution was acidified (pH 3) with concentrated hydrochloric acid in place of 1N hydrochloric acid.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07728131B2uspto-grants-2010_06